The Use of Topical Corticosteroids During Pregnancy

If you are planning a pregnancy or are currently pregnant, it is important to check the safety of your medications. Topical corticosteroids are effective anti-inflammatory agents often prescribed for the treatment of rash and eczema. A recent study* suggests that pregnant women can use topical corticosteroids for short periods of time at normal doses without posing a risk to their child. A group of 2,658 pregnant women ages 15-44 were given one or more prescriptions for topical corticosteroids. Compared to a control group of 7,246 pregnant women who were not exposed, the study revealed no associations between topical corticosteroids and orofacial cleft, low birth weight, preterm delivery, fetal death, low Apgar score nor mode of delivery. It is important to note, however, that further analysis suggests that the use of potent or very potent doses (≥300 g) of corticosteroids during the entire pregnancy may increase the risk for low birth weight.

From Dermatology Times, *original study published online in JAMA Dermatology

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Cleaning Pacifiers with Spit Reduces Later Risk of Eczema

Did you know that cleaning your child’s pacifier with your own saliva may reduce the likelihood that they’ll develop eczema and allergies later on? While it may sound like nasty business, researchers in Sweden reported that an infant’s immune system against eczema, allergies, and asthma is stimulated when parents introduce gut microflora onto the pacifier through their spit. This system works because of the exchange of oral bacteria from parent to child who then swallows the bacteria, which in turn helps to regulate the development of tolerance in their gut.

The study* was conducted among 136 children, all of whom used pacifiers during the first six months. Out of the 136 children, 65 of them had parents who sucked on the pacifiers to clean them. After 18 months, the researchers found that the likelihood of eczema and asthma were reduced in the children who sucked on spit-cleaned pacifiers. This effect held for eczema through the age of 3. It is important to note that spit cleaning had no effect on the transmission of respiratory illnesses from parent to child.

Children also receive these immune system-boosting gut microbes when they pass through the birth canal during a natural vaginal birth. Considering this, researchers recommend that parents who delivered through a cesarean section should at least lick their child’s pacifier because these children are more likely to develop allergies than those delivered by natural birth.

(Journal of Drugs in Dermatology – May 2013)

*http://pediatrics.aappublications.org/content/early/2013/04/30/peds.2012-3345.abstract